Product Name: Mercaptopurine (6-MP)Subtitle: Purine synthesis inhibitorBiological Activity: Biological Activity of Mercaptopurine (6-MP)Inhibitor of de novo purine synthesis through interference with DNA and RNA synthesis. Immunosuppressive and antileukemic drug; reduces…
Product Name: CyclophosphamideSubtitle: Nitrogen mustard alkylating agent and prodrug.Biological Activity: Biological Activity of CyclophosphamideNitrogen mustard alkylating agent and prodrug. Phosphoramide mustard (active metabolite) forms DNA cross-links leading to cell death.…
Product Name: DacarbazineSubtitle: Antineoplastic( malignant melanoma and sarcomas)Biological Activity: SMLES: CN(C)/N=N/C1=C(NC=N1)C(=O)NCAS NO: 112965-21-6Standard In CHIKey: OMJKFYKNWZZKTK-UXBLZVDNSA-NBtk inhibitorsStandard InChI: InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3,11H,1-2H3,(H2,7,13)/b10-6+Typrof Compound: Appearance: Formula: C6H10N6OM.Wt: 182.18General Tips: For obtaining a higher solubility…
Product Name: CladribineSubtitle: Apoptosis inducer in CLL cellsBiological Activity: Biological Activity of CladribineAdenosine deaminase (ADA)-resistant analog of deoxyadenosine. Exhibits anti-leukemic activity; Inhibits cell growth of lymphoid and myeloid neoplasm (IC50…
Product Name: CarboplatinSubtitle: Antitumor agent that forms platinum-DNA adducts.Biological Activity: Biological Activity of CarboplatinAntitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription.…
Product Name: IfosfamideSubtitle: Cytostatic agentBiological Activity: SMLES: C1CN(P(=O)(OC1)NCCCl)CCClCAS NO: 864070-44-0Standard In CHIKey: HOMGKSMUEGBAAB-UHFFFAOYSA-NALK inhibitorsStandard InChI: InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)Typrof Compound: Appearance: Formula: C7H15Cl2N2O2PM.Wt: 261.09General Tips: For obtaining a higher solubility , please warm…
Product Name: EtoposideSubtitle: Topo II inhibitorBiological Activity: Biological Activity of EtoposideTopoisomerase II inhibitor (IC50 = 59.2 μM).SMLES: CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)OCAS NO: 635702-64-6Standard In CHIKey: VJJPUSNTGOMMGY-MRVIYFEKSA-NAck1 inhibitorsStandard InChI: InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1Typrof Compound: Appearance: Formula: C29H32O13M.Wt:…
Product Name: BIBR 1532Subtitle: Telomerase inhibitor,novel and selectiveBiological Activity: Biological Activity of BIBR 1532Selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human…
Product Name: XAV-939Subtitle: Tankyrase 1/2 inhibitorBiological Activity: Biological Activity of XAV-939Potent tankyrase (TNKS) inhibitor (IC50 values are 4 and 11 nM for TNKS2 and TNKS1 respectively). Antagonizes Wnt signaling via…
Product Name: Doxorubicin (Adriamycin) HClSubtitle: Antitumour antibiotic,inhibits TOPO II.Biological Activity: Biological Activity of Doxorubicin (Adriamycin) HClAntitumor antibiotic agent that inhibits DNA topoisomerase II. DNA intercalator that inhibits nucleic acid synthesis…