NECA
Product Name: NECASubtitle: adenosine receptor agonist, non-selectiveBiological Activity: Biological Activity of NECAHigh affinity adenosine receptor agonist (Ki values are 6.2, 14, and 20 nM for human A3, A1 and A2A…
GR 64349
Product Name: GR 64349Subtitle: Biological Activity: Biological Activity of GR 64349Potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Displays > 1000- and > 300-fold…
GR 94800
Product Name: GR 94800Subtitle: Biological Activity: Biological Activity of GR 94800Potent and selective tachykinin NK2 receptor antagonist (pKB values are 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors…
Urotensin II (human)
Product Name: Urotensin II (human)Subtitle: Biological Activity: Biological Activity of Urotensin II (human)Potent endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in…
2-Methylthioadenosine diphosphate trisodium salt
Product Name: 2-Methylthioadenosine diphosphate trisodium saltSubtitle: Biological Activity: Biological Activity of 2-Methylthioadenosine diphosphate trisodium saltPotent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05…
[Orn8]-Urotensin II
Product Name: -Urotensin IISubtitle: Biological Activity: Biological Activity of -Urotensin IIInhibitor of glycogen synthase kinase-3 (GSK-3); derived fromFRAT1, the mammalian version of GSK-3-binding protein. Bindsto GSK-3, inhibiting its interaction with…
Sauvagine
Product Name: SauvagineSubtitle: Biological Activity: Biological Activity of SauvagineCorticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-astressin binding to hCRF-R1, rCRF-R2a and…
CRF (6-33)
Product Name: CRF (6-33)Subtitle: Biological Activity: Biological Activity of CRF (6-33)Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in…
Astressin
Product Name: AstressinSubtitle: Biological Activity: Biological Activity of AstressinPotent corticotropin-releasing factor (CRF) receptor antagonist (Ki values are 2, 1.5 and 1 nM at CRF1, CRF2α and CRF2β). Reduces ACTH secretion,…
Urocortin (rat)
Product Name: Urocortin (rat)Subtitle: Biological Activity: Biological Activity of Urocortin (rat)Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.SMLES: N/ACAS NO: 2012607-27-9Standard…