Product Name: GuanfacineSubtitle: Biological Activity: SMLES: C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)ClCAS NO: 1448232-80-1Standard In CHIKey: DGFYECXYGUIODH-UHFFFAOYSA-NMAPK_ERK Pathway inhibitorsStandard InChI: InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1HTyprof Compound: Appearance: Formula: C9H9Cl2N3OM.Wt: 246.09General Tips: For obtaining a higher solubility , please warm…
Product Name: Almorexant hydrochlorideSubtitle: OX1R/OX2R antagonistBiological Activity: Biological Activity of Almorexant hydrochlorideDescription Almorexant HCl is an orally active, dual antagonist of orexin receptor with IC50 of 6.6 nM and 3.4…
Product Name: AlmorexantSubtitle: OX1R/OX2R antagonistBiological Activity: SMLES: CAS NO: 126105-11-1Standard In CHIKey: EGFR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C29H31F3N2O3M.Wt: 512.56General Tips: For obtaining a higher solubility , please warm…
Product Name: BAF312 (Siponimod)Subtitle: S1P agonist,potent and selectiveBiological Activity: Biological Activity of BAF312 (Siponimod)Description BAF312 is a potent and selective agonist of S1P with EC50 value of 0.39nM for S1P1…
Product Name: TolvaptanSubtitle: AVP V2-receptor antagonistBiological Activity: Biological Activity of TolvaptanPotent and selective competitive vasopressin V2 receptor antagonist (Ki values are 0.06 and 12.3 nM for V2 and V1a receptors…
Product Name: MozavaptanSubtitle: Biological Activity: SMLES: CC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)N3CCCC(C4=CC=CC=C43)N(C)CCAS NO: 1599432-18-4Standard In CHIKey: WRNXUQJJCIZICJ-UHFFFAOYSA-NThrombopoietin Receptor inhibitorsStandard InChI: InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)Typrof Compound: Appearance: Formula: C27H29N3O2M.Wt: 427.54General Tips: For obtaining a higher solubility , please warm…
Product Name: SKI IISubtitle: Sphingosine kinase(SK) inhibitorBiological Activity: Biological Activity of SKI IISelective non-lipid inhibitor of sphingosine kinase (IC50 = 0.5 μM); does not act at ATP-binding site. Displays no…
Product Name: Azilsartan MedoxomilSubtitle: Angiotensin II receptor type 1 antagonistBiological Activity: SMLES: CAS NO: 302803-72-1Standard In CHIKey: SPHK inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C30H24N4O8M.Wt: 568.53General Tips: For obtaining a…
Product Name: ValsartanSubtitle: Angiotensin II AT1 receptor antagonistBiological Activity: Biological Activity of ValsartanHigh affinity AT1 receptor antagonist (Ki = 2.38 nM). Displays 30,000-fold selectivity over AT2 receptors. Inhibits angiotensin II-induced…
Product Name: AzilsartanSubtitle: Biological Activity: Biological Activity of AzilsartanPotent angiotensin II type 1 (AT1) receptor inverse agonist (IC50 = 2.6 nM at the human AT1 receptor). Inhibits angiotensin II-induced IP1…