Product Name: PD123319Subtitle: Angiotensin AT2 receptor antagonistBiological Activity: Biological Activity of PD123319Potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and…
Product Name: PF-05212384 (PKI-587)Subtitle: PI3Kα, PI3Kγ and mTOR inhibitorBiological Activity: Biological Activity of PF-05212384 (PKI-587)Potent and selective dual inhibitor of PI 3-kinase/mTOR (IC50 values are 0.4, 1.6 and 5.4 nM…
Product Name: MRS 2578Subtitle: P2Y6 receptor antagonist,potent and selectiveBiological Activity: Biological Activity of MRS 2578Selective antagonist of P2Y6 nucleotide receptors; IC50 values are 37 and 98 nM at human and…
Product Name: TicagrelorSubtitle: P2Y12 receptor antagonistBiological Activity: SMLES: CCCSC1=NC2=C(C(=N1)NC3CC3C4=CC(=C(C=C4)F)F)N=NN2C5CC(C(C5O)O)OCCOCAS NO: 343306-79-6Standard In CHIKey: Interleukin Related inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C23H28F2N6O4SM.Wt: 522.57General Tips: For obtaining a higher solubility ,…
Product Name: Ticlopidine HClSubtitle: Biological Activity: Biological Activity of Ticlopidine HClSelective P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.SMLES: C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl.ClCAS NO: 162558-52-3Standard…
Product Name: SB408124Subtitle: OX(1)receptor antagonistBiological Activity: Biological Activity of SB408124Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks…
Product Name: DesonideSubtitle: Biological Activity: SMLES: O=C(C()()O)12OC(C()())(C()())O1()C()()((C()()C3())()4()(C()())(C()=C5)C3=C()C5=O)()2(C()())C()()4()OCAS NO: 33289-85-9Standard In CHIKey: WBGKWQHBNHJJPZ-YWZQBGSISA-NCOX inhibitorsStandard InChI: InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15?,16-,17?,19+,20+,22?,23?,24+/m0/s1Typrof Compound: Appearance: Formula: C24H32O6M.Wt: 416.51General Tips: For obtaining a higher solubility , please warm the…
Product Name: AlprostadilSubtitle: Biological Activity: SMLES: CAS NO: 482-44-0Standard In CHIKey: GMVPRGQOIOIIMI-DWKJAMRDSA-NComplement System inhibitorsStandard InChI: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1Typrof Compound: Appearance: Formula: C20H34O5M.Wt: 354.48General Tips: For obtaining a higher solubility , please warm…
Product Name: BimatoprostSubtitle: Biological Activity: SMLES: CAS NO: 482-45-1Standard In CHIKey: AQOKCDNYWBIDND-FTOWTWDKSA-NImmunology_Inflammation inhibitorsStandard InChI: InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1Typrof Compound: Appearance: Formula: C25H37NO4M.Wt: 415.57General Tips: For obtaining a higher solubility , please warm the…
Product Name: Fluticasone propionateSubtitle: Biological Activity: Biological Activity of Fluticasone propionateHigh affinity, selective glucocorticoid receptor agonist (Kd = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances…