Product Name: BYK 49187
Subtitle: Potent PARP-1/PARP-2 inhibitor
Biological Activity: Biological Activity of BYK 49187PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively). Displays potent inhibitory activity against human PARP-1 in cell-free and cellular assays in vitr
SMLES: O=C1CCN2C3=C1C=CC=C3N=C2N4CCC(C5=C(C)N=CN5)CC4
CAS NO: 1639792-20-3
Standard In CHIKey: NF-kappa)B inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H21N5O
M.Wt: 335.4
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/623
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 4,5-Dihydro-2-[4-(4-methyl-1H-imidazol-4-yl)-1-piperidinyl]-6H-imidazo[4,5,1-ij]quinolin-6-one