Product Name: C646
Subtitle: HAT p300-CBP inhibitor,cell-permeable
Biological Activity: Biological Activity of C646Selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM). Selective against six other histone acetyltransferases (HATs). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.
SMLES: CC1=C(C=C(C(=C1)C2=CC=C(O2)C=C3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C)[N+](=O)[O-])C
CAS NO: 1402608-02-9
Standard In CHIKey: TGF-beta) Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H19N3O6
M.Wt: 445.42
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/1175
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid