Product Name: Donepezil HCl
Subtitle: AChE inhibitor
Biological Activity: Biological Activity of Donepezil HClPotent acetylcholinesterase inhibitor (IC50 = 5.7 nM). Displays 1252-fold selectivity for AChE over BuChE (IC50 = 7138 nM for BuChE). Orally active.
SMLES: COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
CAS NO: 1831167-98-6
Standard In CHIKey: XWAIAVWHZJNZQQ-UHFFFAOYSA-NProgesterone Receptor inhibitors
Standard InChI: InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
Typrof Compound:
Appearance:
Formula: C24H30ClNO3
M.Wt: 415.95
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/1213
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in water and to 10 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride