Product Name: G-1
Subtitle: GPR30 agonist, potent and selective
Biological Activity: Biological Activity of G-1Potent and selective GPER agonist (Ki = 11 nM, EC50 = 2 nM); displays no activity at ERα and ERβ at concentrations up to 10 μM. Increases cytosolic Ca2+ and inhibits migration of SKBr3 cells and MCF-7 cells in resp
SMLES: BrC1=C(C=C2OCOC2=C1)[C@H]3NC4=C(C=C(C(C)=O)C=C4)[C@H]5[C@@H]3CC=C5
CAS NO: 1319207-44-7
Standard In CHIKey: 15-PGDH inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H18BrNO3
M.Wt: 412.28
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/1/146
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]- ethanone