Product Name: GSK2656157
Subtitle: PERK inhibitor
Biological Activity: Biological Activity of GSK2656157Description GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with an IC50 value of 0.9 nM. Targets PERK IC50 0.9 nM
SMLES: NC1=NC=NC2=C1C(C3=CC=C4C(CCN4C(CC5=NC(C)=CC=C5)=O)=C3F)=CN2C
CAS NO: 1404456-53-6
Standard In CHIKey: DNA-PK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H21FN6O
M.Wt: 416.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/260/2/437
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone