Product Name: GSK2801
Subtitle: inhibitor of BAZ2A and BAZ2B bromodomains
Biological Activity: Biological Activity of GSK2801Selective BAZ2A and BAZ2B inhibitor (IC50 values are 0.40 and 0.43 μM, respectively). Selective for BAZ2A/B over TAF1L and BRD9. Cell permeable and orally available.
SMLES: CCCOC(C=CN12)=CC2=C(C3=CC=CC=C3S(C)(=O)=O)C=C1C(C)=O
CAS NO: 133052-90-1
Standard In CHIKey: Phenols inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H21NO4S
M.Wt: 371.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/262/1/190
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 1-[1-[2-(Methylsulfonyl)phenyl]-7-propoxy-3-indolizinyl]ethanone