Product Name: Garcinol
Subtitle:
Biological Activity: Biological Activity of GarcinolInhibitor of PCAF and p300 histone acetyltransferase (HAT) activity (IC50 values are 5 and 7 μM, respectively). Promotes expansion of human HSCs ex vivo. Causes reversal of EMT and inhibits β-catenin in breast canc
SMLES: O=C1[C@](C(O)=C2C(C3=CC(O)=C(O)C=C3)=O)(C[C@H](C/C=C(C)/C)C(C)=C)C[C@@H](C/C=C(C)/C)C(C)(C)[C@@]1(C/C=C(C)/C)C2=O
CAS NO: 920509-32-6
Standard In CHIKey: DTTONLKLWRTCAB-BZSUNBQASA-NKinase_Inhibitor_Library inhibitors
Standard InChI: InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-41H,7,13,15,18,20-21H2,1-6,8-10H3/b32-31-/t27-,28+,37+,38-/m0/s1
Typrof Compound:
Appearance:
Formula: C38H50O6
M.Wt: 602.8
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/931
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: (1R,5R,7R)-3-(3,4-Dihydroxybenzyol)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione