Product Name: I-BET-762
Subtitle: BET inhibitor,highly potent
Biological Activity: Biological Activity of I-BET-762Description I-BET-762 is a highly potent inhibitor of bromo and extra C-terminal domain (BET) family with IC50 values of 32.5–42.5 nM. Targets BET IC50 32.5–42.5 nM
SMLES: CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C
CAS NO: 905586-69-8
Standard In CHIKey: YAP inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H22ClN5O2
M.Wt: 423.9
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/1153
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide