Product Name: INCA-6
Subtitle: Selective calcineurin-NFAT signaling inhibitor
Biological Activity: Biological Activity of INCA-6Inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (Kd = 0.8 mM). Inhibits NFAT dephosphorylation a
SMLES: O=C(C=CC1=O)C2=C1[C@@H]3C(C=CC=C4)=C4[C@H]2C5=C3C=CC=C5
CAS NO: 1514888-56-2
Standard In CHIKey: GCHPUOHXXCNSQL-UHFFFAOYSA-NAck1 inhibitors
Standard InChI: InChI=1S/C20H12O2/c21-15-9-10-16(22)20-18-12-6-2-1-5-11(12)17(19(15)20)13-7-3-4-8-14(13)18/h1-10,17-18H
Typrof Compound:
Appearance:
Formula: C20H12O2
M.Wt: 284.31
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/716
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 9,10-Dihydro-9,10[1,2]-benzenoanthracene-1,4-dione