Product Name: IOX 1
Subtitle: histone demethylase JMJD inhibitor
Biological Activity: Biological Activity of IOX 1Histone demethylase JMJD inhibitor (IC50 values are 0.12, 0.17, 0.2, 0.3, 0.6 and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively). Cell permeable; inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa
SMLES: OC1=C2N=CC=CC2=C(C(O)=O)C=C1
CAS NO: 664334-36-5
Standard In CHIKey: NF-κB_Signaling_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C10H7NO3
M.Wt: 189.17
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/970
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in 1eq. NaOH
Storage: Store at +4℃
Purity: >98%
Chemical Name: 8-Hydroxy-5-quinolinecarboxylic acid