Product Name: KC7F2
Subtitle: HIF-1α inhibitor
Biological Activity: Biological Activity of KC7F2Inhibitor of HIF-1α. Thought to act via down-regulation of HIF-1α protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1α
SMLES: C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl
CAS NO: 86-87-3
Standard In CHIKey: Tyrosinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H16Cl4N2O4S4
M.Wt: 570.38
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/518
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: N,N-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide