Product Name: NSC 87877
Subtitle: Shp2 /shp1 PTP inhibitor
Biological Activity: Biological Activity of NSC 87877Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μM for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EG
SMLES: C1=CC2=C(C(=O)C(=NNC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)O)C=C2S(=O)(=O)O)N=C1
CAS NO: 526-18-1
Standard In CHIKey: BIQBDHSYQMHHPU-CJLVFECKSA-Nc-Kit inhibitors
Standard InChI: InChI=1S/C19H13N3O7S2/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13/h1-10,21H,(H,24,25,26)(H,27,28,29)/b22-16+
Typrof Compound:
Appearance:
Formula: C19H13N3O7S2
M.Wt: 459.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/764
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in water and to 20 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonic acid