Product Name: Necrosulfonamide
Subtitle:
Biological Activity: Biological Activity of NecrosulfonamideNecroptosis inhibitor. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex
SMLES: O=S(NC1=NC=CN=C1OC)(C(C=C2)=CC=C2NC(/C=CC3=CC=C([N+]([O-])=O)S3)=O)=O
CAS NO: 926927-61-9
Standard In CHIKey: c-Myc inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H15N5O6S2
M.Wt: 461.47
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/260/1/334
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide