Product Name: PHTPP
Subtitle:
Biological Activity: Biological Activity of PHTPPSelective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ERα. Exhibits full antagonism at ERβ in a cotransfection assay in human endometrial cancer cells (HEC-1), with minimal effects on ERα
SMLES: FC(F)(C1=CC(C(F)(F)F)=NC2=C(C(C=C3)=CC=C3O)C(C4=CC=CC=C4)=NN21)F
CAS NO: 598-02-7
Standard In CHIKey: NEDD8-activating Enzyme inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H11F6N3O
M.Wt: 423.31
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/1/96
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 33 mM in DMSO and to 100 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol