Product Name: PX 12
Subtitle: Trx-1 inhibitor
Biological Activity: Biological Activity of PX 12Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1
SMLES: CCC(C)SSC1=NC=CN1
CAS NO: 1662-01-7
Standard In CHIKey: BPBPYQWMFCTCNG-UHFFFAOYSA-NNeuronal Signaling inhibitors
Standard InChI: InChI=1S/C7H12N2S2/c1-3-6(2)10-11-7-8-4-5-9-7/h4-6H,3H2,1-2H3,(H,8,9)
Typrof Compound:
Appearance:
Formula: C7H12N2S2
M.Wt: 188.31
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/534
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-[(1-Methylpropyl)dithio]-1H-imidazole