Product Name: RU 58668
Subtitle:
Biological Activity: Biological Activity of RU 58668Pure antiestrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM). Displays potent antiproliferative activity in vitro (IC50 = 0.035 – 0.09 nM in MCF-7 cells) and causes long term regression of tamoxifen-res
SMLES: FC(CCCS(=O)(CCCCCOC1=CC=C(C=C1)[C@H]2[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@H](CC5)[C@]([C@H]5O)(C)C2)=O)(C(F)(F)F)F
CAS NO: 137975-06-5
Standard In CHIKey: SDCUWFRXMLQNCS-JGNCIJAKSA-NPhosphodiesterase PDE) inhibitors
Standard InChI: InChI=1S/C34H43F5O5S/c1-32-21-28(31-26-13-9-24(40)20-23(26)8-12-27(31)29(32)14-15-30(32)41)22-6-10-25(11-7-22)44-17-3-2-4-18-45(42,43)19-5-16-33(35,36)34(37,38)39/h6-7,9-11,13,20,27-31,40-41H,2-5,8,12,14-19,21H2,1H3/t27-,28?,29-,30-,31+,32-/m0/s1
Typrof Compound:
Appearance:
Formula: C34H43F5O5S
M.Wt: 658.76
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/2/420
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: (11β,17β)-11-[4-[[5-[(4,4,5,5,5-Pentafluoropentyl)sulfonyl]pentyl]oxy]phenylestra-1,3,5,(10)-triene-3,17-diol