Product Name: SGI-1027
Subtitle: DNMT inhibitor
Biological Activity: Biological Activity of SGI-1027Description SGI-1027 is an inhibitor of DNMT with IC50 values of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively Targets DNMT1 DNMT3B DNMT3A IC50 6 μM 7.5 μM 8 μM
SMLES: CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54
CAS NO: 849675-66-7
Standard In CHIKey: Others inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H23N7O
M.Wt: 461.52
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/1222
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-[4-[(2-amino-6-methylpyrimidin-4-yl)amino]phenyl]-4-(quinolin-4-ylamino)benzamide