Product Name: SMER 28
Subtitle: enhancer of the cytostatic effects
Biological Activity: Biological Activity of SMER 28Positive regulator of autophagy in a mechanism independent from the mTOR pathway. Increases autophagosome synthesis and enhances clearance of model autophagy substrates such as mutant huntingtin and A53T α-synuclein, ass
SMLES: BrC1=CC=C2N=CN=C(C2=C1)NCC=C
CAS NO: 154229-19-3
Standard In CHIKey: PI3K/Akt/mTOR_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C11H10BrN3
M.Wt: 264.12
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/5/385
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6-Bromo-N-2-propenyl-4-quinazolinamine