Product Name: TC-E 5001
Subtitle:
Biological Activity: Biological Activity of TC-E 5001Dual tankyrase (TNKS) inhibitor (Kd values are 79 and 28 nM for TNKS1 and TNKS2 respectively, IC50 = 33 nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC50 >19 μM). Inhibits Wnt signaling and stabili
SMLES: CC(N1C(C=C2)=CC=C2OC)=NN=C1SCC3=NC(C(C=C4)=CC=C4OC)=NO3
CAS NO: 289480-64-4
Standard In CHIKey: Smad_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H19N5O3S
M.Wt: 409.46
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/994
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole