Product Name: Zibotentan (ZD4054)
Subtitle: ETA receptor antagonist,potent and specific
Biological Activity: Biological Activity of Zibotentan (ZD4054)Description Zibotentan (ZD4054) is a specific antagonist of Endothelin (ET)A with an IC50 value of 21 nM. Targets ETA IC50 21 nM
SMLES: CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4
CAS NO:
Standard In CHIKey: DAPK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H16N6O4S
M.Wt: 424.43
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/262/1/375
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide