Product Name: 17-DMAG (Alvespimycin) HCl
Subtitle: Hsp90 inhibitor
Biological Activity: Biological Activity of 17-DMAG (Alvespimycin) HClWater-soluble analog of 17-AAG and geldanamycin. Binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123
SMLES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)C)OC)OC(=O)N)C)C)O)OC.Cl
CAS NO: 0
Standard In CHIKey: Cannabinoid Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C32H48N4O8.HCl
M.Wt: 653.21
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/858
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 30 mM in DMSO and to 10 mM in ethanol
Storage: Desiccate at -20℃
Purity: >98%
Chemical Name: 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin hydrochloride