Product Name: 20(S)-Hydroxycholesterol
Subtitle:
Biological Activity: Biological Activity of 20(S)-HydroxycholesterolAllosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein; binds at a site distinct from the canonical cyclopamine binding site. Activates Hedgehog (Hh) signaling (EC50 ~ 3μM f
SMLES:
CAS NO: 241479-67-4
Standard In CHIKey: MCKLJFJEQRYRQT-APGJSSKUSA-NTAM Receptor inhibitors
Standard InChI: InChI=1S/C27H46O2/c1-18(2)7-6-14-27(5,29)24-11-10-22-21-9-8-19-17-20(28)12-15-25(19,3)23(21)13-16-26(22,24)4/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t20-,21-,22-,23-,24-,25-,26-,27-/m0/s1
Typrof Compound:
Appearance:
Formula: C27H46O2
M.Wt: 402.65
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/3/1316
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: (3β)-Cholest-5-ene-3,20-diol