Product Name: A 887826
Subtitle: voltage-dependent Nav1.8 sodium channel blocker
Biological Activity: Biological Activity of A 887826Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and
SMLES:
CAS NO: 1257426-19-9
Standard In CHIKey: PPAR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H29ClN4O3
M.Wt: 480.99
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/2/976
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 5-(4-Butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl)-3-pyridinyl]methyl-3-pyridine carboxamide