Product Name: AGI-5198
Subtitle: IDH1 inhibitor against R132 mutant,selective and cell-permeable
Biological Activity: Biological Activity of AGI-5198Description AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM. Targets R132H-IDH1 R132C-IDH1 IC50 0.07 μM 0.16 μM
SMLES:
CAS NO: 936091-26-8
Standard In CHIKey: Ribosomal S6 Kinase RSK) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H31FN4O2
M.Wt: 462.56
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/3/955
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility:
Storage:
Purity: >98%
Chemical Name: