Product Name: AR-A014418
Subtitle: GSK3β inhibitor, ATP-competitive and selective
Biological Activity: Biological Activity of AR-A014418Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neur
SMLES:
CAS NO: 1431697-96-9
Standard In CHIKey: FDA-approved_Drug_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C12H12N4O4S
M.Wt: 308.31
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/1/1
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 5 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[(4-Methoxyphenyl)methyl]-N-(5-nitro-2-thiazolyl)urea