Product Name: BMS CCR2 22
Subtitle:
Biological Activity: Biological Activity of BMS CCR2 22High affinity CCR2 chemokine receptor antagonist (IC50 = 5.1 nM). Displays potent functional antagonism, IC50 values are 1 and 18 nM for chemotaxis and antagonism of calcium flux respectively. Selective over CCR3.
SMLES:
CAS NO: 256373-96-3
Standard In CHIKey: Epigenetics_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H34F3N5O4S
M.Wt: 593.66
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/265/3/1429
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide