Product Name: BYL-719
Subtitle: Selective PI3Kα inhibitor
Biological Activity: Biological Activity of BYL-719Description BYL719 is a potent and selective inhibitor of PI3Kα with IC50 of 5 nM. Targets PI3Kα IC50 5 nM
SMLES: CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F
CAS NO: 1801747-11-4
Standard In CHIKey: AMPK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H22F3N5O2S
M.Wt: 441.47
General Tips: for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/830
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide