Product Name: Brivanib Alaninate (BMS-582664)
Subtitle: VEGFR2 inhibitor,ATP-competitive
Biological Activity: Biological Activity of Brivanib Alaninate (BMS-582664)Description Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with IC50 value of 25 nM. Targets VEGFR2 IC50 25 nM
SMLES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)OC(=O)C(C)N)C
CAS NO: 1346572-63-1
Standard In CHIKey: KLF inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H24FN5O4
M.Wt: 441.46
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/265
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate