Product Name: Capsazepine
Subtitle: TRPV1 ion channel activator
Biological Activity: Biological Activity of CapsazepineSelective vanilloid receptor antagonist (Ki = 3.2 μM). Inhibits carrageenan inflammation-induced hyperalgesic responses in the rat. Also activates amiloride-sensitive epithelial Na+ channel ENaCδ. Also available
SMLES: c1cc(ccc1CCNC(=S)N2CCCc3cc(c(cc3C2)O)O)Cl
CAS NO: 1352608-82-2
Standard In CHIKey: DRCMAZOSEIMCHM-UHFFFAOYSA-NCytoskeleton inhibitors
Standard InChI: InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)
Typrof Compound:
Appearance:
Formula: C19H21ClN2O2S
M.Wt: 376.9
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/258/2/676
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in ethanol and to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide