Product Name: Cediranib (AZD217)
Subtitle: VEGFR inhibitor receptor,highly potent
Biological Activity: Biological Activity of Cediranib (AZD217)Description Cediranib is a highly potent inhibitor of VEGFR with IC50 value of <1 nM. Targets VEGFR2/KDR c-Kit VEGFR3/FLT4 VEGFR1/FLT1 PDGFRβ FGFR1 IC50 0.5 nM 2 nM ≤3 nM 5 nM 5 nM 26 nM
SMLES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5
CAS NO: 937263-43-9
Standard In CHIKey: SPHK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H27FN4O3
M.Wt: 450.51
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/198
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: Cediranib