Product Name: EC 144
Subtitle:
Biological Activity: Biological Activity of EC 144High affinity, potent and selective Hsp90 inhibitor (Ki = 0.2 nM and IC50 = 1.1 nM). Exhibits selectivity for Hsp90 over Grp94 and TRAP1 (Ki values are 61 and 255 nM respectively) and has no effect (IC50 >10 μM) agai
SMLES: ClC1=C2C(N(CC3=C(C)C(OC)=C(C)C=N3)C=C2C#CCC(O)(C)C)=NC(N)=N1
CAS NO: 14534-61-3
Standard In CHIKey: NF-κB inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H24ClN5O2
M.Wt: 413.9
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/3/1267
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 5-[2-Amino-4-chloro-7-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-methyl-4-pentyn-2-ol