Product Name: Evacetrapib (LY2484595)
Subtitle: CETP inhibitor,potent and selective
Biological Activity: Biological Activity of Evacetrapib (LY2484595)Description Evacetrapib is a potent and selective inhibitor of cholesterylester transfer protein (CETP) with IC50 value of 5.5 nM. Targets CETP IC50 5.5 nM
SMLES: CC1=CC(=C2C(=C1)C(CCCN2CC3CCC(CC3)C(=O)O)N(CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=NN(N=N5)C)C
CAS NO: 1532533-67-7
Standard In CHIKey: Neuropeptide Y Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C31H36F6N6O2
M.Wt: 638.65
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/266/3/1177
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[[(5S)-5-[[3,5-bis(trifluoromethyl)phenyl]methyl-(2-methyltetrazol-5-yl)amino]-7,9-dimethyl-2,3,4,5-tetrahydro-1-benzazepin-1-yl]methyl]cyclohexane-1-carboxylic acid