Product Name: GDC-0623
Subtitle: MEK1 inhibitor, potent and ATP-uncompetitive
Biological Activity: Biological Activity of GDC-0623Description GDC-0623 is a potent and ATP-uncompetitive inhibitor of MEK1 with Ki value of 0.13 nM. Targets MEK1 IC50 0.13 nM (Ki)
SMLES: C1=CC(=C(C=C1I)F)NC2=C(C=CC3=CN=CN32)C(=O)NOCCO
CAS NO: 1532533-67-7
Standard In CHIKey: Checkpoint Kinase Chk) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H14FIN4O3
M.Wt: 456.21
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/459
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 5-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide