Product Name: GW791343 HCl
Subtitle: P2X7 allosteric modulator
Biological Activity: Biological Activity of GW791343 HClP2X7 allosteric modulator. Exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 – 7.2) and a positive allosteric modulator of rat P2X7.
SMLES: CC1=C(C=C(C=C1)CN2CCNCC2)NC(=O)CNC3=CC(=C(C=C3)F)F.Cl.Cl.Cl
CAS NO: 105558-26-7
Standard In CHIKey: MAGL inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H27Cl3F2N4O
M.Wt: 483.81
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/268/3/1476
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide trihydrochloride