Product Name: Gefitinib
Subtitle: Selective EGFR inhibitor
Biological Activity: Biological Activity of Gefitinib Orally active, selective inhibitor of EGFR tyrosine kinase (IC50 = 23 – 79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearin
SMLES: COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4
CAS NO: 1341224-83-6
Standard In CHIKey: XGALLCVXEZPNRQ-UHFFFAOYSA-NTrk Receptor inhibitors
Standard InChI: InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
Typrof Compound: Alkaloids
Appearance: Powder
Formula: C22H24ClFN4O3
M.Wt: 446.9
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/1024
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage: Store at RT
Purity: ≥98%
Chemical Name: