Product Name: Golvatinib (E7050)
Subtitle: C-Met/VEGFR-2 inhibitor
Biological Activity: Biological Activity of Golvatinib (E7050)Description Golvatinib (E7050) is a dual inhibitor of c-Met and VEGFR-2 with IC50 values of 14 nM and 16 nM, respectively. Targets c-Met VEGFR2 IC50 14 nM 16 nM
SMLES: CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
CAS NO: 1094067-13-6
Standard In CHIKey: JNK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C33H37F2N7O4
M.Wt: 633.69
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/254
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-N-[2-fluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide