Product Name: INK 128 (MLN0128)
Subtitle: MTOR(TORC-1/-2) inhibitor,potent and selective
Biological Activity: Biological Activity of INK 128 (MLN0128)Description INK 128 (MLN0128) is a potent and selective inhibitor of mTOR with an IC50 value of 1 nM. Targets mTOR PI3Kα PI3Kγ PI3Kδ PI3Kβ IC50 1 nM (Ki=1.4 nM) 219 nM 221 nM 230 nM 5293 nM
SMLES: CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N
CAS NO: 1037624-75-1
Standard In CHIKey: GPCR_G Protein inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C15H15N7O
M.Wt: 309.33
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/895
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine