Product Name: Ki20227
Subtitle: C-Fms tyrosine kinase inhibitor
Biological Activity: Biological Activity of Ki20227Inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R) (IC50 values are 2, 12, 217 and 451 nM for c-Fms, VEGFR-2, PDGFRβ and c-Kit respectively). Does not inhibit Flt3, EGFR or c-Src. Suppresses osteoclast differentiation an
SMLES: CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
CAS NO: 1393465-84-3
Standard In CHIKey: ATGL inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H24N4O5S
M.Wt: 480.55
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/2/508
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N-[1-(2-thiazolyl)ethyl]urea