Product Name: LDE225 (NVP-LDE225,Erismodegib)
Subtitle: Smoothened inhibitor,potent and selective
Biological Activity: Biological Activity of LDE225 (NVP-LDE225,Erismodegib)Description LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC50 values of 2.5 nM and 1.3 nM for human Hedgehog and mouse Hedgehog, respectively. Targets human Hedgehog mo
SMLES: CC1CN(CC(O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F
CAS NO: 214766-78-6
Standard In CHIKey: MALT1 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H26F3N3O3
M.Wt: 485.5
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/3/1043
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl]-2-methyl-3-[4-(trifluoromethoxy)phenyl]benzamide