Product Name: Lenvatinib (E7080)
Subtitle: VEGFR inhibitor
Biological Activity: Biological Activity of Lenvatinib (E7080)Description Lenvatinib is an inhibitor of multiple RTK with IC50 values of 22 nM, 4 nM, 5.2 nM, 39 nM and 35 nM on VEGFR-1, VEGFR-2, VEGFR-3, PDGFRβ and RET, respectively. Targets VEGFR-1 VEGFR-2 VEGFR-3
SMLES: COc1cc2c(cc1C(=O)N)c(ccn2)Oc3ccc(c(c3)Cl)NC(=O)NC4CC4
CAS NO: 1849590-01-7
Standard In CHIKey: Toll-like Receptor TLR) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H19ClN4O4
M.Wt: 426.85
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/219
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: Lenvatinib