Product Name: MK 571
Subtitle: leukotriene D4 receptor antagonist, orally active
Biological Activity: Biological Activity of MK 571Potent CysLT1 (LTD4) leukotriene receptor inverse agonist (EC50 = 1.3 nM). Antagonizes LTD4-induced contractions of guinea pig trachea and ileum (pA2 values are 9.4 and 10.5 respectively). Also inhibitor of multidrug resistanc
SMLES: ClC1=CC=C2C(N=C(C=C2)/C=C/C3=CC([C@@H](SCCC(O)=O)SCCC(N(C)C)=O)=CC=C3)=C1
CAS NO: 609799-22-6
Standard In CHIKey: AXUZQJFHDNNPFG-UXBLZVDNSA-NKeap1-Nrf2 inhibitors
Standard InChI: InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+
Typrof Compound:
Appearance:
Formula: C26H27ClN2O3S2
M.Wt: 515.09
General Tips: for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/265/2/801
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid