Product Name: ML 289
Subtitle:
Biological Activity: Biological Activity of ML 289Selective negative allosteric modulator at mGlu3 receptors (IC50 = 660 nM). Exhibits 15-fold selectivity for mGlu3 over mGlu2. Centrally penetrant.
SMLES: OC[C@@H]1CCCN(C(C2=CC=C(C#CC(C=C3)=CC=C3OC)C=C2)=O)C1
CAS NO: 1197953-54-0
Standard In CHIKey: Phosphatase_Inhibitor_Cocktail_II inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H23NO3
M.Wt: 349.42
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/269/2/823
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: [(3R)-3-(Hydroxymethyl)-1-pipridinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone