Product Name: NPS-2143 hydrochloride
Subtitle: Calcium ion-sensing receptor antagonist
Biological Activity: Biological Activity of NPS-2143 hydrochlorideSelective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43 nM). Also stimulates parathyroid hormone sec
SMLES: CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl
CAS NO: 1639042-08-2
Standard In CHIKey: Ser_Thr Protease inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H26Cl2N2O2
M.Wt: 445.38
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/2/400
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benzonitrile hydrochloride