Product Name: Niclosamide
Subtitle:
Biological Activity: Biological Activity of NiclosamideInhibitor of the STAT3 signaling pathway; inhibits the activation, nuclear translocation and transactivation of STAT3. Displays selectivity for STAT3 over STAT1, STAT5, JAK1, JAK2 and Src kinases. Inhibits the transcripti
SMLES: C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
CAS NO: 1197953-54-0
Standard In CHIKey: RJMUSRYZPJIFPJ-UHFFFAOYSA-NKinase_Inhibitor_Library inhibitors
Standard InChI: InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)
Typrof Compound:
Appearance:
Formula: C13H8Cl2N2O4
M.Wt: 327.12
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/982
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in ethanol and to 10 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide