Product Name: OSI-420
Subtitle: EGFR inhibitor
Biological Activity: Biological Activity of OSI-420Description OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). Targets EGFR IC50
SMLES: COCCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCO.Cl
CAS NO: 1255580-76-7
Standard In CHIKey: Immunology/Inflammation_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H22ClN3O4
M.Wt: 415.87
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/971
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol;hydrochloride