Product Name: Oprozomib (ONX-0912)
Subtitle: Proteasome inhibitor
Biological Activity: Biological Activity of Oprozomib (ONX-0912)Description Oprozomib (ONX 0912) is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5 and LMP7 with IC50 values of 36 nM and 82 nM, respectively. Targets 20S proteasome β5 20S protea
SMLES: Cc1ncc(s1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@]3(CO3)C
CAS NO: 60166-93-0
Standard In CHIKey: Smo inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H32N4O7S
M.Wt: 532.61
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/3/1388
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: Oprozomib